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Anti-Pseudomonas aeruginosa impA Polyclonal Antibody (JN076034)

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Vista general
Número de catálogoJN076034
Descripción
Anti-Pseudomonas aeruginosa impA Polyclonal Antibody (JN076034) is a rabbit polyclonal antibody detecting IMPa. Suitable for Pseudomonas aeruginosa.
Reactividad de especiesPseudomonas aeruginosa
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Pseudomonas aeruginosa impA (Ala42-Pro923).
Objetivo EC:3.4.24.-, IMPa, Immunomodulating metalloprotease, impA
Nivel de endotoxinas Please contact with the lab for this information.
Purificación Purified by antigen affinity column.
Número de acceso Q9I5W4
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Fondo

Immunomodulating metalloprotease (impA) is a ~100 kDa protein. Protease that degrades several proteins of the host immune system. Cleaves P-selectin glycoprotein ligand-1 (PSGL-1), leading to its functional inhibition; PSGL-1 is a leukocyte cell-surface receptor essential for leukocyte recruitment to the site of infection. Next to PSGL-1, targets host CD43 and CD44 that are also involved in leukocyte homing. Thus, prevents neutrophil extravasation and thereby protects P.aeruginosa from neutrophil attack. Is also able to inhibit the decay accelerating factor (CD55), but not the cell-surface receptors CD46 and CD31.

Nota For research use only
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