

| Numéro de catalogue | HB158014 | ||||||||
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| Description |
Anti-PSMC3 Polyclonal Antibody (HB158014) is a rabbit polyclonal antibody detecting PSMC3 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, and Xenopus laevis.
Highlights
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| Reactivité des espèces | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human PSMC3 (Asn2-Ala439). | ||||||||
| Cible | 26S proteasome AAA-ATPase subunit RPT5, Tat-binding protein 1, Proteasome 26S subunit ATPase 3, Proteasome subunit P50, 26S proteasome regulatory subunit 6A, TBP-1, PSMC3, TBP1 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | P17980 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | 26S proteasome regulatory subunit 6A (PSMC3) is a ~49 kDa protein. Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC3 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides. | ||||||||
| Note | For research use only. |
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