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| カタログ番号 | HX951014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-PSMC6 Polyclonal Antibody (HX951014) is a rabbit polyclonal antibody detecting PSMC6 in ELISA, IHC, WB. Suitable for Bovine, Human, and Mouse.
Highlights
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| 種反応性 | Human, Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human PSMC6 (Met1-Val389). | ||||||||
| ターゲット | SUG2, 26S proteasome AAA-ATPase subunit RPT4, 26S proteasome regulatory subunit 10B, Proteasome subunit p42, Proteasome 26S subunit ATPase 6, PSMC6 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P62333 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | 26S proteasome regulatory subunit 10B (PSMC6) is a ~44 kDa protein. Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC6 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides. | ||||||||
| 注意事項 | For research use only. |
Western blot analysis was performed using anti-PSMC6 polyclonal antibody at 1ug/mL on various samples.
Lane 1: 293T cell lysate
Lane 2: SH-SY5Y cell lysate
Lane 3: NCI-H460 cell lysate
Lane 4: Hela cell lysate
Lane 5: HepG2 cell lysate
Lane 6: Mouse brain lysate
Lane 7: Mouse liver lysate
Lane 8: Mouse spleen lysate
Lane 9: Mouse kidney lysate
Lane 10: Rat brain lysate
Lane11: Rat liver lysate
Lane12: Rat spleen lysate
Lane13: Rat kidney lysate
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