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| カタログ番号 | HX247014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-PSMD4 Polyclonal Antibody (HX247014) is a rabbit polyclonal antibody detecting PSMD4 in ELISA, IHC, WB. Suitable for Human, Mouse, and Bovine.
Highlights
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| 種反応性 | Human, Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human PSMD4 (Met1-Lys377). | ||||||||
| ターゲット | 26S proteasome regulatory subunit S5A, MCB1, 26S proteasome regulatory subunit RPN10, ASF, Multiubiquitin chain-binding protein, PSMD4, 26S proteasome non-ATPase regulatory subunit 4, AF, Antisecretory factor 1 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P55036 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | 26S proteasome non-ATPase regulatory subunit 4 (PSMD4) is a ~40 kDa protein. Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMD4 acts as an ubiquitin receptor subunit through ubiquitin-interacting motifs and selects ubiquitin-conjugates for destruction. Displays a preferred selectivity for longer polyubiquitin chains. | ||||||||
| 注意事項 | For research use only. |
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