

| Каталожный номер | HX247014 | ||||||||
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| Описание |
Anti-PSMD4 Polyclonal Antibody (HX247014) is a rabbit polyclonal antibody detecting PSMD4 in ELISA, IHC, WB. Suitable for Human, Mouse, and Bovine.
Highlights
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| Реактивность видов | Human, Mouse | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Human PSMD4 (Met1-Lys377). | ||||||||
| Цель | 26S proteasome regulatory subunit S5A, MCB1, 26S proteasome regulatory subunit RPN10, ASF, Multiubiquitin chain-binding protein, PSMD4, 26S proteasome non-ATPase regulatory subunit 4, AF, Antisecretory factor 1 | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | P55036 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | 26S proteasome non-ATPase regulatory subunit 4 (PSMD4) is a ~40 kDa protein. Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMD4 acts as an ubiquitin receptor subunit through ubiquitin-interacting motifs and selects ubiquitin-conjugates for destruction. Displays a preferred selectivity for longer polyubiquitin chains. | ||||||||
| Примечание | For research use only. |
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