Anti-PTGDS Polyclonal Antibody (HW677014)

Name: Anti-PTGDS Polyclonal Antibody
Brand: abinScience
SKU: HW677014
Price: 96 USD
Availability: InStock

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SDS

Aperçu

Numéro de catalogue

HW677014

Description

Anti-PTGDS Polyclonal Antibody (HW677014) is a rabbit polyclonal antibody detecting PTGDS in ELISA, IHC, WB. Suitable for Human and Pongo pygmaeus.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Reactivité des espèces

Human

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human PTGDS (Pro32-Gln190).

Cible

Prostaglandin-H2 D-isomerase, PGDS2, PGD2 synthase, Prostaglandin-D2 synthase, PGDS, Cerebrin-28, L-PGDS, PDS, Beta-trace protein, Glutathione-independent PGD synthase, Lipocalin-type prostaglandin-D synthase, PTGDS

Purification

Purified by antigen affinity column.

Numéro d'accès

P41222

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Prostaglandin-H2 D-isomerase (PTGDS) is a ~21 kDa protein. Catalyzes the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation. Involved in a variety of CNS functions, such as sedation, NREM sleep and PGE2-induced allodynia, and may have an anti-apoptotic role in oligodendrocytes. Binds small non-substrate lipophilic molecules, including biliverdin, bilirubin, retinal, retinoic acid and thyroid hormone, and may act as a scavenger for harmful hydrophobic molecules and as a secretory retinoid and thyroid hormone transporter. Possibly involved in development and maintenance of the blood-brain, blood-retina, blood-aqueous humor and blood-testis barrier. It is likely to play important roles in both maturation and maintenance of the central nervous system and male reproductive system.

1. Zhou, Y. et al. (2010) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 24, 4668-77. PMID: 20667974

2. Tokugawa, Y. et al. (1998) Biology of reproduction 58, 600-7. PMID: 9475419

Note

For research use only.

Images

Reférences

Fiche technique

Anti-PTGDS Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

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