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| カタログ番号 | HW677014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-PTGDS Polyclonal Antibody (HW677014) is a rabbit polyclonal antibody detecting PTGDS in ELISA, IHC, WB. Suitable for Human and Pongo pygmaeus.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human PTGDS (Pro32-Gln190). | ||||||||
| ターゲット | Prostaglandin-H2 D-isomerase, PGDS2, PGD2 synthase, Prostaglandin-D2 synthase, PGDS, Cerebrin-28, L-PGDS, PDS, Beta-trace protein, Glutathione-independent PGD synthase, Lipocalin-type prostaglandin-D synthase, PTGDS | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P41222 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Prostaglandin-H2 D-isomerase (PTGDS) is a ~21 kDa protein. Catalyzes the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation. Involved in a variety of CNS functions, such as sedation, NREM sleep and PGE2-induced allodynia, and may have an anti-apoptotic role in oligodendrocytes. Binds small non-substrate lipophilic molecules, including biliverdin, bilirubin, retinal, retinoic acid and thyroid hormone, and may act as a scavenger for harmful hydrophobic molecules and as a secretory retinoid and thyroid hormone transporter. Possibly involved in development and maintenance of the blood-brain, blood-retina, blood-aqueous humor and blood-testis barrier. It is likely to play important roles in both maturation and maintenance of the central nervous system and male reproductive system. 1. Zhou, Y. et al. (2010) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 24, 4668-77. PMID: 20667974 2. Tokugawa, Y. et al. (1998) Biology of reproduction 58, 600-7. PMID: 9475419 | ||||||||
| 注意事項 | For research use only. |
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