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Anti-PTGES2 Polyclonal Antibody (HV079014)

Anti-PTGES2 Polyclonal Antibody
Anti-PTGES2 Polyclonal Antibody
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  • 概要

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  • データシート

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概要
カタログ番号HV079014
説明
Anti-PTGES2 Polyclonal Antibody (HV079014) is a rabbit polyclonal antibody detecting PTGES2 in ELISA, IHC, WB. Suitable for Human, Mouse, Bovine, and Macaca fascicularis.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
種反応性Human
アプリケーションELISA, IHC, WB
宿主種Rabbit
クローン性Polyclonal
アイソタイプIgG
免疫原 E. coli - derived recombinant Human PTGES2 (Tyr145-Thr357).
ターゲット Microsomal prostaglandin E synthase 2, PGES2, Membrane-associated prostaglandin E synthase-2, Prostaglandin E synthase 2, Prostaglandin-H(2) E-isomerase, C9orf15, mPGES-2, mPGE synthase-2, PTGES2
精製 Purified by antigen affinity column.
アクセッション番号 Q9H7Z7
形態 Liquid
保存バッファー 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

製品使用情報
アプリケーション 希釈
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
安定性と保存 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Prostaglandin E synthase 2 (PTGES2) is a ~41 kDa protein. Isomerase that catalyzes the conversion of PGH2 into the more stable prostaglandin E2 (PGE2) (in vitro). The biological function and the GSH-dependent property of PTGES2 is still under debate. In vivo, PTGES2 could form a complex with GSH and heme and would not participate in PGE2 synthesis but would catalyze the degradation of prostaglandin E2 H2 (PGH2) to 12(S)-hydroxy-5(Z),8(E),10(E)-heptadecatrienoic acid (HHT) and malondialdehyde (MDA).

1. Watanabe, K. et al. (2003) Biochemical and biophysical research communications 306, 577-81. PMID: 12804604
2. Yamada, T. et al. (2007) Biochemistry 46, 8414-24. PMID: 17585783
3. Watanabe, K. et al. (2008) Biochemical and biophysical research communications 367, 782-6. PMID: 18198127
注意事項 For research use only.
イメージ
  • Anti-PTGES2 Polyclonal Antibody

    Western blot

    Western blot analysis was performed using anti-PTGES2 polyclonal antibody at 1ug/mL on various samples.
    Lane 1: Mouse heart lysate
    Lane 2: Rat heart lysate

参考文献
Formula
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