

| カタログ番号 | HV079014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-PTGES2 Polyclonal Antibody (HV079014) is a rabbit polyclonal antibody detecting PTGES2 in ELISA, IHC, WB. Suitable for Human, Mouse, Bovine, and Macaca fascicularis.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human PTGES2 (Tyr145-Thr357). | ||||||||
| ターゲット | Microsomal prostaglandin E synthase 2, PGES2, Membrane-associated prostaglandin E synthase-2, Prostaglandin E synthase 2, Prostaglandin-H(2) E-isomerase, C9orf15, mPGES-2, mPGE synthase-2, PTGES2 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q9H7Z7 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Prostaglandin E synthase 2 (PTGES2) is a ~41 kDa protein. Isomerase that catalyzes the conversion of PGH2 into the more stable prostaglandin E2 (PGE2) (in vitro). The biological function and the GSH-dependent property of PTGES2 is still under debate. In vivo, PTGES2 could form a complex with GSH and heme and would not participate in PGE2 synthesis but would catalyze the degradation of prostaglandin E2 H2 (PGH2) to 12(S)-hydroxy-5(Z),8(E),10(E)-heptadecatrienoic acid (HHT) and malondialdehyde (MDA). 1. Watanabe, K. et al. (2003) Biochemical and biophysical research communications 306, 577-81. PMID: 12804604 2. Yamada, T. et al. (2007) Biochemistry 46, 8414-24. PMID: 17585783 3. Watanabe, K. et al. (2008) Biochemical and biophysical research communications 367, 782-6. PMID: 18198127 | ||||||||
| 注意事項 | For research use only. |

Western blot analysis was performed using anti-PTGES2 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse heart lysate
Lane 2: Rat heart lysate


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