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Anti-PTGIS Polyclonal Antibody (MS772014)

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Aperçu
Numéro de catalogueMS772014
Description
Anti-PTGIS Polyclonal Antibody (MS772014) is a rabbit polyclonal antibody detecting Prostacyclin synthase; 5.3.99.4; Hydroperoxy icosatetraenoate dehydratase; 4.2.1.152; Prostaglandin I2 synthase; Ptgis; Cyp8 in ELISA, IHC, WB. Suitable for Mouse, Human, and Rat.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactivité des espècesMouse, Rat
ApplicationsELISA, IHC, WB
Espèce hôteRabbit
ClonalitéPolyclonal
IsotypeIgG
Immunogène E. coli - derived recombinant mouse PTGIS (Gly42-Leu501).
Cible Prostacyclin synthase; 5.3.99.4; Hydroperoxy icosatetraenoate dehydratase; 4.2.1.152; Prostaglandin I2 synthase; Ptgis; Cyp8
Niveau d'endotoxines Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Numéro d'accès Q16647, O35074, Q62969
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Informations d'utilisation du produit
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte

Prostacyclin synthase (PTGIS) is a ~57 kDa protein. Catalyzes the biosynthesis and metabolism of eicosanoids. Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2), a potent mediator of vasodilation and inhibitor of platelet aggregation. Additionally, displays dehydratase activity, toward hydroperoxyeicosatetraenoates (HPETEs), especially toward (15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate (15(S)-HPETE).

1. Nakayama, T. et al. (2002) Biochemical and biophysical research communications 297, 1135-9. PMID: 12372404
2. Wada, M. et al. (2004) Journal of biochemistry 135, 455-63. PMID: 15115769
3. Li, YC. et al. (2008) The Journal of biological chemistry 283, 2917-26. PMID: 18032380
4. Cho, SA. et al. (2015) Archives of biochemistry and biophysics 569, 10-8. PMID: 25623425
5. Yeh, HC. et al. (2007) Archives of biochemistry and biophysics 461, 159-68. PMID: 17459323
Note For research use only
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-PTGIS Polyclonal Antibody

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