

| Numéro de catalogue | HB946014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-PTPN1 Polyclonal Antibody (HB946014) is a rabbit polyclonal antibody detecting PTPN1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, and Chicken.
Highlights
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| Reactivité des espèces | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human PTPN1 (Met1-Asn321). | ||||||||
| Cible | PTPN1, PTP-1B, Tyrosine-protein phosphatase non-receptor type 1, Protein-tyrosine phosphatase 1B, PTP1B | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | P18031 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Tyrosine-protein phosphatase non-receptor type 1 (PTPN1) is a ~49 kDa protein. Tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response. Mediates dephosphorylation of EIF2AK3/PERK; inactivating the protein kinase activity of EIF2AK3/PERK. May play an important role in CKII- and p60c-src-induced signal transduction cascades. May regulate the EFNA5-EPHA3 signaling pathway which modulates cell reorganization and cell-cell repulsion. May also regulate the hepatocyte growth factor receptor signaling pathway through dephosphorylation of MET. | ||||||||
| Note | For research use only. |

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Lane 2: MCF-7 cell lysate
Lane 3: A549 cell lysate
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