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Anti-PTPRM Polyclonal Antibody (HB921014)

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Vista general
Número de catálogoHB921014
Descripción
Anti-PTPRM Polyclonal Antibody (HB921014) is a rabbit polyclonal antibody detecting PTPRM in ELISA, IHC, WB. Suitable for Human and Mouse.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Reactividad de especiesHuman, Mouse
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human PTPRM (Thr1197-Ser1403).
Objetivo Protein-tyrosine phosphatase mu, R-PTP-mu, PTPRL1, PTPRM, Receptor-type tyrosine-protein phosphatase mu
Purificación Purified by antigen affinity column.
Número de acceso P28827
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Receptor-type tyrosine-protein phosphatase mu (PTPRM) is a ~163 kDa protein. Receptor protein-tyrosine phosphatase that mediates homotypic cell-cell interactions and plays a role in adipogenic differentiation via modulation of p120 catenin/CTNND1 phosphorylation. Promotes CTNND1 dephosphorylation and prevents its cytoplasmic localization where it inhibits SLC2A4 membrane trafficking. In turn, SLC2A4 is directed to the plasma membrane and performs its glucose transporter function.

1. Zondag, GC. et al. (2000) The Journal of biological chemistry 275, 11264-9. PMID: 10753936
2. Aricescu, AR. et al. (2007) Science (New York, N.Y.) 317, 1217-20. PMID: 17761881
3. Kim, WK. et al. (2011) Molecular biology of the cell 22, 4883-91. PMID: 21998202
Nota For research use only.
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Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-PTPRM Polyclonal Antibody

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