Anti-PTPRS Polyclonal Antibody (HC306014)

Name: Anti-PTPRS Polyclonal Antibody
Brand: abinScience
SKU: HC306014
Price: 168 USD
Availability: InStock

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Especificación:

50ug
100ug

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HC306014

Reactividad de especies

Human, Mouse, Rat

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant Human PTPRS (Arg77-Gly374).

Objetivo

R-PTP-S, PTPRS, Receptor-type tyrosine-protein phosphatase S, R-PTP-sigma, Receptor-type tyrosine-protein phosphatase sigma

Purificación

Purified by antigen affinity column.

Número de acceso

Q13332

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Receptor-type tyrosine-protein phosphatase S (PTPRS) is a ~217 kDa protein. Cell surface receptor that binds to glycosaminoglycans, including chondroitin sulfate proteoglycans and heparan sulfate proteoglycan. Binding to chondroitin sulfate and heparan sulfate proteoglycans has opposite effects on PTPRS oligomerization and regulation of neurite outgrowth. Contributes to the inhibition of neurite and axonal outgrowth by chondroitin sulfate proteoglycans, also after nerve transection. Plays a role in stimulating neurite outgrowth in response to the heparan sulfate proteoglycan GPC2. Required for normal brain development, especially for normal development of the pituitary gland and the olfactory bulb.

1. Coles, CH. et al. (2011) Science (New York, N.Y.) 332, 484-8. PMID: 21454754

2. Pulido, R. et al. (1995) Proceedings of the National Academy of Sciences of the United States of America 92, 11686-90. PMID: 8524829

3. Bunin, A. et al. (2015) Immunity 43, 277-88. PMID: 26231120

Nota

For research use only.

Imágenes

Referencias

Datasheet

Anti-PTPRS Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

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