

| Numéro de catalogue | HS786014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-QPCT Polyclonal Antibody (HS786014) is a rabbit polyclonal antibody detecting QPCT in ELISA, IHC, WB. Suitable for Bovine and Human.
Highlights
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human QPCT (Val29-Leu361). | ||||||||
| Cible | sQC, Glutaminyl-tRNA cyclotransferase, QC, QPCT, Glutamyl cyclase, EC, Glutaminyl-peptide cyclotransferase, Glutaminyl cyclase | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q16769 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Glutaminyl-peptide cyclotransferase (QPCT) is a ~40 kDa protein. Responsible for the biosynthesis of pyroglutamyl peptides. Has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue. Also catalyzes N-terminal pyroglutamate formation. In vitro, catalyzes pyroglutamate formation of N-terminally truncated form of APP amyloid-beta peptides [Glu-3]-amyloid-beta. May be involved in the N-terminal pyroglutamate formation of several amyloid-related plaque-forming peptides. | ||||||||
| Note | For research use only. |
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