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| カタログ番号 | HS786014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-QPCT Polyclonal Antibody (HS786014) is a rabbit polyclonal antibody detecting QPCT in ELISA, IHC, WB. Suitable for Bovine and Human.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human QPCT (Val29-Leu361). | ||||||||
| ターゲット | sQC, Glutaminyl-tRNA cyclotransferase, QC, QPCT, Glutamyl cyclase, EC, Glutaminyl-peptide cyclotransferase, Glutaminyl cyclase | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q16769 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Glutaminyl-peptide cyclotransferase (QPCT) is a ~40 kDa protein. Responsible for the biosynthesis of pyroglutamyl peptides. Has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue. Also catalyzes N-terminal pyroglutamate formation. In vitro, catalyzes pyroglutamate formation of N-terminally truncated form of APP amyloid-beta peptides [Glu-3]-amyloid-beta. May be involved in the N-terminal pyroglutamate formation of several amyloid-related plaque-forming peptides. | ||||||||
| 注意事項 | For research use only. |
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