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Anti-RAB1A Polyclonal Antibody (HX207014)

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Aperçu
Numéro de catalogueHX207014
Description
Anti-RAB1A Polyclonal Antibody (HX207014) is a rabbit polyclonal antibody detecting RAB1A in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactivité des espècesHuman, Mouse, Rat
ApplicationsELISA, IHC, WB
Espèce hôteRabbit
ClonalitéPolyclonal
IsotypeIgG
Immunogène E. coli - derived recombinant Human RAB1A (Met1-Cys205).
Cible Ras-related protein Rab-1A, YPT1-related protein, RAB1A, RAB1
Purification Purified by antigen affinity column.
Numéro d'accès P62820
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Informations d'utilisation du produit
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte

Ras-related protein Rab-1A (RAB1A) is a ~22 kDa protein. The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB1A regulates vesicular protein transport from the endoplasmic reticulum (ER) to the Golgi compartment and on to the cell surface, and plays a role in IL-8 and growth hormone secretion. Required to modulate the compacted morphology of the Golgi. Regulates the level of CASR present at the cell membrane.

1. Wang, C. et al. (2010) The Journal of biological chemistry 285, 29398-405. PMID: 20639577
2. Zhuang, X. et al. (2010) Endocrinology 151, 5114-23. PMID: 20861236
3. Mukhopadhyay, A. et al. (2011) Journal of cell science 124, 765-75. PMID: 21303926
4. Dong, N. et al. (2012) Cell 150, 1029-41. PMID: 22939626
5. Aizawa, M. et al. (2015) The Journal of biological chemistry 290, 22250-61. PMID: 26209634
Note For research use only.
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Reférences
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-RAB1A Polyclonal Antibody

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