

| Каталожный номер | HX207014 | ||||||||
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| Описание |
Anti-RAB1A Polyclonal Antibody (HX207014) is a rabbit polyclonal antibody detecting RAB1A in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
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| Реактивность видов | Human, Mouse, Rat | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Human RAB1A (Met1-Cys205). | ||||||||
| Цель | Ras-related protein Rab-1A, YPT1-related protein, RAB1A, RAB1 | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | P62820 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | Ras-related protein Rab-1A (RAB1A) is a ~22 kDa protein. The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB1A regulates vesicular protein transport from the endoplasmic reticulum (ER) to the Golgi compartment and on to the cell surface, and plays a role in IL-8 and growth hormone secretion. Required to modulate the compacted morphology of the Golgi. Regulates the level of CASR present at the cell membrane. 1. Wang, C. et al. (2010) The Journal of biological chemistry 285, 29398-405. PMID: 20639577 2. Zhuang, X. et al. (2010) Endocrinology 151, 5114-23. PMID: 20861236 3. Mukhopadhyay, A. et al. (2011) Journal of cell science 124, 765-75. PMID: 21303926 4. Dong, N. et al. (2012) Cell 150, 1029-41. PMID: 22939626 5. Aizawa, M. et al. (2015) The Journal of biological chemistry 290, 22250-61. PMID: 26209634 | ||||||||
| Примечание | For research use only. |
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