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| カタログ番号 | HW332014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-RAB28 Polyclonal Antibody (HW332014) is a rabbit polyclonal antibody detecting RAB28 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Pongo abelii.
Highlights
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| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human RAB28 (Met1-Ile95). | ||||||||
| ターゲット | Ras-related protein Rab-28, RAB28 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P51157 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Ras-related protein Rab-28 (RAB28) is a ~24 kDa protein. The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB28 is required for shedding and phagocytosis of cone cell outer segments (OS) discs in the retina. Also participates in nuclear factor kappa-B p65/RELA nuclear transport in endothelial cells. 1. Brauers, A. et al. (1996) European journal of biochemistry 237, 833-40. PMID: 8647132 | ||||||||
| 注意事項 | For research use only. |
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