Anti-Rabies virus G/Glycoprotein Recombinant Antibody (17C7) (VK584013)

Name: Anti-Rabies virus G/Glycoprotein Recombinant Antibody (17C7)
Brand: abinScience
SKU: VK584013
Price: 126 USD
Availability: InStock

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1mg

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Aperçu
Images
Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

VK584013

Reactivité des espèces

Rabies virus (RABV)

Applications

ELISA, Neutralization

Espèce hôte

Human

Clonalité

Monoclonal

Isotype

IgG1, kappa

ID de clone

17C7

Cible

G, Glycoprotein

Niveau d'endotoxines

Please contact with the lab for this information.

Pureté

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

P03524

RRID

Anti-Rabies virus G/Glycoprotein Antibody (17C7) (abinScience Cat# VK584013, RRID:AB_3725279)

Forme

Liquid

Tampon de stockage

0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:2000-1:20000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Contexte

Glycoprotein is a ~58 kDa protein. Attaches the virus to host cellular receptor, inducing endocytosis of the virion by using different host proteins including TFRC, GRM2 and ITGB1. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells.

Note

For research use only.

Images

Bioactivity

SEC-HPLC detection for Anti-Rabies virus G/Glycoprotein Antibody (17C7).
SDS-PAGE

SDS-PAGE for Anti-Rabies virus G/Glycoprotein Antibody (17C7).
Bioactivity

Detects Recombinant RABV G/Glycoprotein, C-His (Cat No.: VK584011) in indirect ELISA.