

| Numéro de catalogue | VK632324 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Rabies virus/RABV G/Glycoprotein Polyclonal Antibody, Biotin (VK632324) is a rabbit polyclonal antibody detecting Glycoprotein in WB, IHC, ELISA.
Highlights
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| Reactivité des espèces | Rabies virus (RABV) | ||||||||
| Applications | WB, IHC, ELISA | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Conjugaison | Biotin | ||||||||
| Immunogène | E. coli - derived recombinant Rabies virus/RABV G/Glycoprotein (Leu30-Tyr459). | ||||||||
| Cible | G, Glycoprotein | ||||||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||||||
| Pureté | >90% as determined by SDS-PAGE. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | O92284 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. | ||||||||
| Expédition | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. | ||||||||
| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Glycoprotein is a ~58 kDa protein. Attaches the virus to host cellular receptor, inducing endocytosis of the virion by using different host proteins including TFRC, GRM2 and ITGB1. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells. | ||||||||
| Note | For research use only. |




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