

| Número de catálogo | VK632014 | ||||||||
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| Descripción |
Anti-Rabies virus/RABV G/Glycoprotein Polyclonal Antibody (VK632014) is a rabbit polyclonal antibody detecting Glycoprotein in ELISA, IHC, WB. Suitable for Rabies virus.
Highlights
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| Reactividad de especies | Rabies virus (RABV) | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Rabies virus/RABV G/Glyco(Leu30-Tyr459). | ||||||||
| Aplicaciones probadas | WB | ||||||||
| Objetivo | Glycoprotein, G | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | O92284 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Glycoprotein is a ~58 kDa protein. Attaches the virus to host cellular receptor, inducing endocytosis of the virion by using different host proteins including TFRC, GRM2 and ITGB1. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells. | ||||||||
| Nota | For research use only. |

Western blot analysis was performed using anti-RABV-G polyclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant Rabies virus/RABV G/Glycoprotein (Catalog No: VK632012)




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