

| カタログ番号 | VK632014 | ||||||||
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| 説明 |
Anti-Rabies virus/RABV G/Glycoprotein Polyclonal Antibody (VK632014) is a rabbit polyclonal antibody detecting Glycoprotein in ELISA, IHC, WB. Suitable for Rabies virus.
Highlights
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| 種反応性 | Rabies virus (RABV) | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Rabies virus/RABV G/Glyco(Leu30-Tyr459). | ||||||||
| テスト済みアプリケーション | WB | ||||||||
| ターゲット | Glycoprotein, G | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | O92284 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Glycoprotein is a ~58 kDa protein. Attaches the virus to host cellular receptor, inducing endocytosis of the virion by using different host proteins including TFRC, GRM2 and ITGB1. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells. | ||||||||
| 注意事項 | For research use only. |

Western blot analysis was performed using anti-RABV-G polyclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant Rabies virus/RABV G/Glycoprotein (Catalog No: VK632012)


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