

| Каталожный номер | VK632014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-Rabies virus/RABV G/Glycoprotein Polyclonal Antibody (VK632014) is a rabbit polyclonal antibody detecting Glycoprotein in ELISA, IHC, WB. Suitable for Rabies virus.
Highlights
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| Реактивность видов | Rabies virus (RABV) | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Rabies virus/RABV G/Glyco(Leu30-Tyr459). | ||||||||
| Проверенные приложения | WB | ||||||||
| Цель | Glycoprotein, G | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | O92284 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | Glycoprotein is a ~58 kDa protein. Attaches the virus to host cellular receptor, inducing endocytosis of the virion by using different host proteins including TFRC, GRM2 and ITGB1. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells. | ||||||||
| Примечание | For research use only. |

Western blot analysis was performed using anti-RABV-G polyclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant Rabies virus/RABV G/Glycoprotein (Catalog No: VK632012)




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