

| Número de catálogo | HV665014 | ||||||||
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| Descripción |
Anti-RAD54L2 Polyclonal Antibody (HV665014) is a rabbit polyclonal antibody detecting RAD54L2 in ELISA, IHC, WB. Suitable for Human and Mouse.
Highlights
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| Reactividad de especies | Human, Mouse | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human RAD54L2 (Ala638-Ser837). | ||||||||
| Objetivo | Androgen receptor-interacting protein 4, KIAA0809, Helicase ARIP4, ARIP4, RAD54L2, RAD54-like protein 2 | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | Q9Y4B4 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Helicase ARIP4 (RAD54L2) is a ~162 kDa protein. Helicase that modulates androgen receptor (AR)-dependent transactivation in a promoter-dependent manner. May stimulate the release of RNA polymerase II, that has paused near the transcription start sites of AR-targeted genes and unwind R-loops formed at these sites; R-loops result from the hybridization of the short RNA strand nascently synthesized by the paused RNA polymerase II molecule and the DNA template. May also stimulate double-strand break formation by TOP2B, which appears important for transcriptional output. Not able to remodel mononucleosomes in vitro. 1. Ng, RR. et al. (2024) Science advances 10, eadm9577. PMID: 39028815 | ||||||||
| Nota | For research use only. |
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