

| Каталожный номер | HV665014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-RAD54L2 Polyclonal Antibody (HV665014) is a rabbit polyclonal antibody detecting RAD54L2 in ELISA, IHC, WB. Suitable for Human and Mouse.
Highlights
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| Реактивность видов | Human, Mouse | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Human RAD54L2 (Ala638-Ser837). | ||||||||
| Цель | Androgen receptor-interacting protein 4, KIAA0809, Helicase ARIP4, ARIP4, RAD54L2, RAD54-like protein 2 | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | Q9Y4B4 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | Helicase ARIP4 (RAD54L2) is a ~162 kDa protein. Helicase that modulates androgen receptor (AR)-dependent transactivation in a promoter-dependent manner. May stimulate the release of RNA polymerase II, that has paused near the transcription start sites of AR-targeted genes and unwind R-loops formed at these sites; R-loops result from the hybridization of the short RNA strand nascently synthesized by the paused RNA polymerase II molecule and the DNA template. May also stimulate double-strand break formation by TOP2B, which appears important for transcriptional output. Not able to remodel mononucleosomes in vitro. 1. Ng, RR. et al. (2024) Science advances 10, eadm9577. PMID: 39028815 | ||||||||
| Примечание | For research use only. |
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