Anti-RALA Polyclonal Antibody (HY266014)

Name: Anti-RALA Polyclonal Antibody
Brand: abinScience
SKU: HY266014
Price: 168 USD
Availability: InStock

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概要
イメージ
参考文献
データシート
SDS

概要

カタログ番号

HY266014

説明

Anti-RALA Polyclonal Antibody (HY266014) is a rabbit polyclonal antibody detecting RALA in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, and Saguinus oedipus.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

種反応性

Human, Mouse, Rat

アプリケーション

ELISA, IHC, WB

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

免疫原

E. coli - derived recombinant Human RALA (Met1-Leu206).

ターゲット

Ras-related protein Ral-A, RAL, RALA

精製

Purified by antigen affinity column.

アクセッション番号

P11233

形態

Liquid

保存バッファー

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

製品使用情報

アプリケーション	希釈
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

安定性と保存

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Ras-related protein Ral-A (RALA) is a ~23 kDa protein. Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles. The RALA-exocyst complex regulates integrin-dependent membrane raft exocytosis and growth signaling. Key regulator of LPAR1 signaling and competes with GRK2 for binding to LPAR1 thus affecting the signaling properties of the receptor.

1. Cascone, I. et al. (2008) The EMBO journal 27, 2375-87. PMID: 18756269

2. Aziziyeh, AI. et al. (2009) Cellular signalling 21, 1207-17. PMID: 19306925

3. Balasubramanian, N. et al. (2010) Current biology : CB 20, 75-9. PMID: 20005108

4. Kashatus, DF. et al. (2011) Nature cell biology 13, 1108-15. PMID: 21822277

5. Hiatt, SM. et al. (2018) PLoS genetics 14, e1007671. PMID: 30500825

注意事項

For research use only.

イメージ

参考文献

データシート

Anti-RALA Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

組換えタンパク質

抗体

アッセイキット

Anti-RALA Polyclonal Antibody (HY266014)

概要

イメージ

参考文献

データシート

SDS