

| Каталожный номер | HY266014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-RALA Polyclonal Antibody (HY266014) is a rabbit polyclonal antibody detecting RALA in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, and Saguinus oedipus.
Highlights
|
||||||||
| Реактивность видов | Human, Mouse, Rat | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Human RALA (Met1-Leu206). | ||||||||
| Цель | Ras-related protein Ral-A, RAL, RALA | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | P11233 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
||||||||
| Информация об использовании продукта |
| ||||||||
| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | Ras-related protein Ral-A (RALA) is a ~23 kDa protein. Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles. The RALA-exocyst complex regulates integrin-dependent membrane raft exocytosis and growth signaling. Key regulator of LPAR1 signaling and competes with GRK2 for binding to LPAR1 thus affecting the signaling properties of the receptor. 1. Cascone, I. et al. (2008) The EMBO journal 27, 2375-87. PMID: 18756269 2. Aziziyeh, AI. et al. (2009) Cellular signalling 21, 1207-17. PMID: 19306925 3. Balasubramanian, N. et al. (2010) Current biology : CB 20, 75-9. PMID: 20005108 4. Kashatus, DF. et al. (2011) Nature cell biology 13, 1108-15. PMID: 21822277 5. Hiatt, SM. et al. (2018) PLoS genetics 14, e1007671. PMID: 30500825 | ||||||||
| Примечание | For research use only. |
Свяжитесь с нами для индивидуальных предложений, оптовых запросов и других вопросов.
Почта: [email protected]
Быстрый доступ
Свяжитесь с нами
+86-027-65523339
Building C, No. 666, Shen Dun Si Lu, Wuhan, 430206, China
中文
English
한국어
日本語
Español
Français
Русский