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Anti-RALBP1 Polyclonal Antibody (HS735014)

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Vista general
Número de catálogoHS735014
Descripción
Anti-RALBP1 Polyclonal Antibody (HS735014) is a rabbit polyclonal antibody detecting RalBP1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, and Xenopus laevis.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactividad de especiesHuman, Mouse, Rat
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human RALBP1 (Arg403-Met499).
Objetivo Dinitrophenyl S-glutathione ATPase, RLIP1, RalBP1, DNP-SG ATPase, 76 kDa Ral-interacting protein, Ral-interacting protein 1, RalA-binding protein 1, RLIP76, RALBP1
Purificación Purified by antigen affinity column.
Número de acceso Q15311
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

RalA-binding protein 1 (RALBP1) is a ~76 kDa protein. Multifunctional protein that functions as a downstream effector of RALA and RALB. As a GTPase-activating protein/GAP can inactivate CDC42 and RAC1 by stimulating their GTPase activity. As part of the Ral signaling pathway, may also regulate ligand-dependent EGF and insulin receptors-mediated endocytosis. During mitosis, may act as a scaffold protein in the phosphorylation of EPSIN/EPN1 by the mitotic kinase cyclin B-CDK1, preventing endocytosis during that phase of the cell cycle. During mitosis, also controls mitochondrial fission as an effector of RALA.

1. Jullien-Flores, V. et al. (1995) The Journal of biological chemistry 270, 22473-7. PMID: 7673236
2. Jullien-Flores, V. et al. (2000) Journal of cell science 113 ( Pt 16), 2837-44. PMID: 10910768
3. Rossé, C. et al. (2003) The Journal of biological chemistry 278, 30597-604. PMID: 12775724
4. Kashatus, DF. et al. (2011) Nature cell biology 13, 1108-15. PMID: 21822277
Nota For research use only.
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Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-RALBP1 Polyclonal Antibody

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