Anti-RALBP1 Polyclonal Antibody (HS735014)

Name: Anti-RALBP1 Polyclonal Antibody
Brand: abinScience
SKU: HS735014
Price: 168 USD
Availability: InStock

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SDS

Aperçu

Numéro de catalogue

HS735014

Description

Anti-RALBP1 Polyclonal Antibody (HS735014) is a rabbit polyclonal antibody detecting RalBP1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, and Xenopus laevis.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Reactivité des espèces

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human RALBP1 (Arg403-Met499).

Cible

Dinitrophenyl S-glutathione ATPase, RLIP1, RalBP1, DNP-SG ATPase, 76 kDa Ral-interacting protein, Ral-interacting protein 1, RalA-binding protein 1, RLIP76, RALBP1

Purification

Purified by antigen affinity column.

Numéro d'accès

Q15311

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

RalA-binding protein 1 (RALBP1) is a ~76 kDa protein. Multifunctional protein that functions as a downstream effector of RALA and RALB. As a GTPase-activating protein/GAP can inactivate CDC42 and RAC1 by stimulating their GTPase activity. As part of the Ral signaling pathway, may also regulate ligand-dependent EGF and insulin receptors-mediated endocytosis. During mitosis, may act as a scaffold protein in the phosphorylation of EPSIN/EPN1 by the mitotic kinase cyclin B-CDK1, preventing endocytosis during that phase of the cell cycle. During mitosis, also controls mitochondrial fission as an effector of RALA.

1. Jullien-Flores, V. et al. (1995) The Journal of biological chemistry 270, 22473-7. PMID: 7673236

2. Jullien-Flores, V. et al. (2000) Journal of cell science 113 ( Pt 16), 2837-44. PMID: 10910768

3. Rossé, C. et al. (2003) The Journal of biological chemistry 278, 30597-604. PMID: 12775724

4. Kashatus, DF. et al. (2011) Nature cell biology 13, 1108-15. PMID: 21822277

Note

For research use only.

Images

Reférences

Fiche technique

Anti-RALBP1 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

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