

| Número de catálogo | HB393014 | ||||||||
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| Descripción |
Anti-RANGAP1 Polyclonal Antibody (HB393014) is a rabbit polyclonal antibody detecting Ran GTPase-activating protein 1; RanGAP1; RANGAP1; KIAA1835; SD in ELISA, IHC, WB. Suitable for Human and Mouse.
Highlights
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| Reactividad de especies | Human, Mouse | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant human RANGAP1 (Gly21-Asp360). | ||||||||
| Objetivo | Ran GTPase-activating protein 1; RanGAP1; RANGAP1; KIAA1835; SD | ||||||||
| Nivel de endotoxinas | Please contact with the lab for this information. | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | P46060, P46061 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Ran GTPase-activating protein 1 (RANGAP1) is a ~63 kDa protein. GTPase activator for RAN. Converts cytoplasmic GTP-bound RAN to GDP-bound RAN, which is essential for RAN-mediated nuclear import and export. Mediates dissociation of cargo from nuclear export complexes containing XPO1, RAN and RANBP2 after nuclear export. 1. Takeda, E. et al. (2005) Cell structure and function 30, 69-80. PMID: 16428860 2. Bischoff, FR. et al. (1994) Proceedings of the National Academy of Sciences of the United States of America 91, 2587-91. PMID: 8146159 3. Görlich, D. et al. (1996) The EMBO journal 15, 5584-94. PMID: 8896452 4. Ritterhoff, T. et al. (2016) Nature communications 7, 11482. PMID: 27160050 | ||||||||
| Nota | For research use only |
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