

| Numéro de catalogue | HB393014 | ||||||||
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| Description |
Anti-RANGAP1 Polyclonal Antibody (HB393014) is a rabbit polyclonal antibody detecting Ran GTPase-activating protein 1; RanGAP1; RANGAP1; KIAA1835; SD in ELISA, IHC, WB. Suitable for Human and Mouse.
Highlights
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| Reactivité des espèces | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant human RANGAP1 (Gly21-Asp360). | ||||||||
| Cible | Ran GTPase-activating protein 1; RanGAP1; RANGAP1; KIAA1835; SD | ||||||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | P46060, P46061 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Ran GTPase-activating protein 1 (RANGAP1) is a ~63 kDa protein. GTPase activator for RAN. Converts cytoplasmic GTP-bound RAN to GDP-bound RAN, which is essential for RAN-mediated nuclear import and export. Mediates dissociation of cargo from nuclear export complexes containing XPO1, RAN and RANBP2 after nuclear export. 1. Takeda, E. et al. (2005) Cell structure and function 30, 69-80. PMID: 16428860 2. Bischoff, FR. et al. (1994) Proceedings of the National Academy of Sciences of the United States of America 91, 2587-91. PMID: 8146159 3. Görlich, D. et al. (1996) The EMBO journal 15, 5584-94. PMID: 8896452 4. Ritterhoff, T. et al. (2016) Nature communications 7, 11482. PMID: 27160050 | ||||||||
| Note | For research use only |
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