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| カタログ番号 | RC372014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Rat C1QBP Polyclonal Antibody (RC372014) is a rabbit polyclonal antibody detecting C1QBP in ELISA, IHC, WB. Suitable for Rattus norvegicus, Mus musculus, Human, and Bovine.
Highlights
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| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Rat C1QBP (Leu72-Gln279(Thr210Ala)). | ||||||||
| ターゲット | C1QBP | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | O35796 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 別名 | Complement component 1 Q subcomponent-binding protein, mitochondrial, GC1q-R protein, Glycoprotein gC1qBP, C1qBP, C1qbp, Gc1qbp | ||||||||
| 背景 | Complement component 1 Q subcomponent-binding protein, mitochondrial (C1QBP) is a ~30 kDa protein. Multifunctional and multicompartmental protein involved in inflammation and infection processes, ribosome biogenesis, protein synthesis in mitochondria, regulation of apoptosis, transcriptional regulation and pre-mRNA splicing. At the cell surface is thought to act as an endothelial receptor for plasma proteins of the complement and kallikrein-kinin cascades. Putative receptor for C1q; specifically binds to the globular 'heads' of C1q thus inhibiting C1; may perform the receptor function through a complex with C1qR/CD93. In complex with cytokeratin-1/KRT1 is a high affinity receptor for kininogen-1/HMWK. Can also bind other plasma proteins, such as coagulation factor XII leading to its autoactivation. | ||||||||
| 注意事項 | For research use only. |
Western blot analysis was performed using anti-C1QBP polyclonal antibody at 1ug/mL on various samples.
Lane 1: Hela cell lysate
Lane 2: Jurkat cell lysate
Lane 3: K562 cell lysate
Lane 4: PC-12 cell lysate
Lane 5: C2C12 cell lysate
Lane 6: A549 cell lysate
Lane 7: Mouse spleen lysate
Lane 8: Mouse lung lysate
Lane 9: Rat spleen lysate
Lane 10: Rat lung lysate
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