

| Numéro de catalogue | RP768014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Rat Mbl1 Polyclonal Antibody (RP768014) is a rabbit polyclonal antibody detecting Mbl1 in ELISA, IHC, WB. Suitable for Rat.
Highlights
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| Reactivité des espèces | Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Rat Mbl1 (Gly86-Ala238). | ||||||||
| Cible | Mannose-binding protein A, MBP-A, Mannan-binding protein, Mbl1 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | P19999 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Mannose-binding protein A (Mbl1) is a ~25 kDa protein. Calcium-dependent lectin. Plays a role in the innate immune response by binding mannose, fucose and N-acetylglucosamine moieties on different microorganisms and mediating activation of the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. 1. Ng, KK. et al. (2002) The Journal of biological chemistry 277, 16088-95. PMID: 11850428 2. Weis, WI. et al. (1992) Nature 360, 127-34. PMID: 1436090 3. Ng, KK. et al. (1997) Biochemistry 36, 979-88. PMID: 9033386 4. Ikeda, K. et al. (1987) The Journal of biological chemistry 262, 7451-4. PMID: 3584121 | ||||||||
| Note | For research use only. |
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