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| カタログ番号 | HW462014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-RCVRN Polyclonal Antibody (HW462014) is a rabbit polyclonal antibody detecting RCVRN in ELISA, IHC, WB. Suitable for Human, Mouse, Dog, and Bovine.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human RCVRN (Gly2-Ala200). | ||||||||
| ターゲット | RCVRN, Recoverin, RCV1, Cancer-associated retinopathy protein, Protein CAR | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P35243 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Recoverin (RCVRN) is a ~23 kDa protein. Acts as a calcium sensor and regulates phototransduction of cone and rod photoreceptor cells. Modulates light sensitivity of cone photoreceptor in dark and dim conditions. In response to high Ca(2+) levels induced by low light levels, prolongs RHO/rhodopsin activation in rod photoreceptor cells by binding to and inhibiting GRK1-mediated phosphorylation of RHO/rhodopsin. Plays a role in scotopic vision/enhances vision in dim light by enhancing signal transfer between rod photoreceptors and rod bipolar cells. Improves rod photoreceptor sensitivity in dim light and mediates response of rod photoreceptors to facilitate detection of change and motion in bright light. | ||||||||
| 注意事項 | For research use only. |
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