

| Número de catálogo | HY021014 | ||||||||
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| Descripción |
Anti-RHO Polyclonal Antibody (HY021014) is a rabbit polyclonal antibody detecting Rhodopsin; Opsin-2; RHO; OPN2 in ELISA, IHC, WB. Suitable for Human, Dog, Pig, Cat, and Mouse.
Highlights
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| Reactividad de especies | Human, Mouse, Rat | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant human RHO (Asn2-Gln36&Thr97-Cys110&Gly174-Ser202). | ||||||||
| Objetivo | Rhodopsin; Opsin-2; RHO; OPN2 | ||||||||
| Nivel de endotoxinas | Please contact with the lab for this information. | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | P08100, P32308, O18766, Q95KU1, P15409, P02700, P51489, P02699, P29403, P28683, P49912 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Rhodopsin is a ~38 kDa protein. Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of the chromophore 11-cis-retinal to all-trans-retinal triggers a conformational change that activates signaling via G-proteins. Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by the arrestin SAG and terminates signaling. 1. Sieving, PA. et al. (1995) Proceedings of the National Academy of Sciences of the United States of America 92, 880-4. PMID: 7846071 2. Rao, VR. et al. (1994) Nature 367, 639-42. PMID: 8107847 3. Noorwez, SM. et al. (2003) The Journal of biological chemistry 278, 14442-14450. PMID: 12566452 4. Dryja, TP. et al. (1990) The New England journal of medicine 323, 1302-7. PMID: 2215617 5. Kang, Y. et al. (2015) Nature 523, 561-7. PMID: 26200343 6. He, Y. et al. (2017) Cell research 27, 728-747. PMID: 28524165 7. Zhou, XE. et al. (2017) Cell 170, 457-469.e13. PMID: 28753425 | ||||||||
| Nota | For research use only |
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