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Anti-RNASE7 Polyclonal Antibody (HV262014)

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Vista general
Número de catálogoHV262014
Descripción
Anti-RNASE7 Polyclonal Antibody (HV262014) is a rabbit polyclonal antibody detecting RNASE7 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Reactividad de especiesHuman
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human RNASE7 (Lys31-Val155).
Objetivo Skin-derived antimicrobial protein 2, RNASE7, Ribonuclease 7, RNase 7, SAP-2
Purificación Purified by antigen affinity column.
Número de acceso Q9H1E1
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Ribonuclease 7 (RNASE7) is a ~17 kDa protein. Exhibits a potent RNase activity. Has broad-spectrum antimicrobial activity against many pathogenic microorganisms including uropathogenic E.coli (UPEC), and remarkably potent activity (lethal dose of 90% < 30 nM) against a vancomycin resistant Enterococcus faecium. Causes loss of bacterial membrane integrity. Probably contributes to urinary tract sterility. Bactericidal activity is independent of RNase activity.

1. Harder, J. et al. (2002) The Journal of biological chemistry 277, 46779-84. PMID: 12244054
2. Zhang, J. et al. (2003) Nucleic acids research 31, 602-7. PMID: 12527768
3. Huang, YC. et al. (2007) The Journal of biological chemistry 282, 4626-4633. PMID: 17150966
4. Becknell, B. et al. (2015) Kidney international 87, 151-61. PMID: 25075772
5. Bender, K. et al. (2021) American journal of physiology. Renal physiology 320, F972-F983. PMID: 33818125
Nota For research use only.
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Referencias
Datasheet
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-RNASE7 Polyclonal Antibody

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