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| カタログ番号 | HB475014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-RNF19B Polyclonal Antibody (HB475014) is a rabbit polyclonal antibody detecting E3 ubiquitin-protein ligase RNF19B; 2.3.2.31; IBR domain-containing protein 3; Natural killer lytic-associated molecule; RING finger protein 19B; RNF19B; IBRDC3; NKLAM in ELISA, IHC, WB. Suitable for Human and Mouse.
Highlights
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| 種反応性 | Human, Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant human RNF19B (Ala114-Ser323). | ||||||||
| ターゲット | E3 ubiquitin-protein ligase RNF19B; 2.3.2.31; IBR domain-containing protein 3; Natural killer lytic-associated molecule; RING finger protein 19B; RNF19B; IBRDC3; NKLAM | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q6ZMZ0, A2A7Q9 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | E3 ubiquitin-protein ligase RNF19B is a ~77 kDa protein. E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates, such as UCKL1. Involved in the cytolytic activity of natural killer cells and cytotoxic T-cells. Protects against staurosporin-induced cell death. 1. Fortier, JM. et al. (2006) Journal of immunology (Baltimore, Md. : 1950) 176, 6454-63. PMID: 16709802 2. Kaneko, M. et al. (2016) Scientific reports 6, 30955. PMID: 27485036 3. Kozlowski, M. et al. (1999) Journal of immunology (Baltimore, Md. : 1950) 163, 1775-85. PMID: 10438909 | ||||||||
| 注意事項 | For research use only |
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