

| Número de catálogo | HA773014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-RNF220 Polyclonal Antibody (HA773014) is a rabbit polyclonal antibody detecting E3 ubiquitin-protein ligase RNF220; 2.3.2.27; RING finger protein 220; RING-type E3 ubiquitin transferase RNF220; RNF220; C1orf164 in ELISA, IHC, WB. Suitable for Human, Bovine, and Mouse.
Highlights
|
||||||||
| Reactividad de especies | Human, Mouse | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant human RNF220 (Lys482-Leu566). | ||||||||
| Objetivo | E3 ubiquitin-protein ligase RNF220; 2.3.2.27; RING finger protein 220; RING-type E3 ubiquitin transferase RNF220; RNF220; C1orf164 | ||||||||
| Nivel de endotoxinas | Please contact with the lab for this information. | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | Q5VTB9, Q08DV5, Q6PDX6 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
||||||||
| Información de uso del producto |
| ||||||||
| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | E3 ubiquitin-protein ligase RNF220 is a ~62 kDa protein. E3 ubiquitin-protein ligase that promotes the ubiquitination and proteasomal degradation of SIN3B. Independently of its E3 ligase activity, acts as a CTNNB1 stabilizer through USP7-mediated deubiquitination of CTNNB1 promoting Wnt signaling. Plays a critical role in the regulation of nuclear lamina. 1. Ma, P. et al. (2014) Molecular and cellular biology 34, 4355-66. PMID: 25266658 2. Sferra, A. et al. (2021) Brain : a journal of neurology 144, 3020-3035. PMID: 33964137 | ||||||||
| Nota | For research use only |
Contáctenos para cotizaciones personalizadas, solicitudes en masa y cualquier otro problema.
Correo: [email protected]
Acceso rápido
Contáctenos
+86-027-65523339
Edificio C, No. 666, Calle Shendunsi, Wuhan, 430206, China
中文
English
한국어
日本語
Español
Français
Русский