

| カタログ番号 | HB576014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-RNMT Polyclonal Antibody (HB576014) is a rabbit polyclonal antibody detecting mRNA cap guanine-N7 methyltransferase; 2.1.1.56; RG7MT1; mRNA (guanine-N(7))-methyltransferase; mRNA cap methyltransferase; hCMT1; hMet; hcm1p; RNMT; KIAA0398 in ELISA, IHC, WB. Suitable for Human, Rat, and Mouse.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant human RNMT (Gly144-Gln476). | ||||||||
| ターゲット | mRNA cap guanine-N7 methyltransferase; 2.1.1.56; RG7MT1; mRNA (guanine-N(7))-methyltransferase; mRNA cap methyltransferase; hCMT1; hMet; hcm1p; RNMT; KIAA0398 | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | O43148, Q5U2U7, Q9D0L8 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | mRNA cap guanine-N(7) methyltransferase (RNMT) is a ~54 kDa protein. Catalytic subunit of the mRNA-capping methyltransferase RNMT:RAMAC complex that methylates the N7 position of the added guanosine to the 5'-cap structure of mRNAs. Binds RNA containing 5'-terminal GpppC. 1. Saha, N. et al. (1999) The Journal of biological chemistry 274, 16553-62. PMID: 10347220 2. Wen, Y. et al. (2000) Genes & development 14, 2944-9. PMID: 11114884 3. Gonatopoulos-Pournatzis, T. et al. (2011) Molecular cell 44, 585-96. PMID: 22099306 4. Varshney, D. et al. (2016) Nucleic acids research 44, 10423-10436. PMID: 27422871 5. Pillutla, RC. et al. (1998) The Journal of biological chemistry 273, 21443-6. PMID: 9705270 6. Tsukamoto, T. et al. (1998) Biochemical and biophysical research communications 251, 27-34. PMID: 9790902 | ||||||||
| 注意事項 | For research use only |
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