

| Каталожный номер | HY271014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-RPN1 Polyclonal Antibody (HY271014) is a rabbit polyclonal antibody detecting RPN1 in ELISA, IHC, WB. Suitable for Human, Mouse, Dog, Rat, and Macaca fascicularis.
Highlights
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| Реактивность видов | Human, Mouse, Rat | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Human RPN1 (Ala24-Ser179). | ||||||||
| Цель | RPN1, RPN-I, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit, Ribophorin I, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1, Ribophorin-1 | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | P04843 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (RPN1) is a ~68 kDa protein. Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. 1. Ramírez, AS. et al. (2019) Science (New York, N.Y.) 366, 1372-1375. PMID: 31831667 | ||||||||
| Примечание | For research use only. |
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