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Anti-RTN4R/NgR1/Nogor Recombinant Antibody (M5) (HP096013)

Anti-RTN4R/NgR1/Nogor Recombinant Antibody (M5)
Anti-RTN4R/NgR1/Nogor Recombinant Antibody (M5)
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概要
カタログ番号HP096013
説明
Anti-RTN4R/NgR1/Nogor Recombinant Antibody (M5) (HP096013) is a human monoclonal antibody detecting RTN4R/NgR1/Nogor in ELISA, FCM, IF, IP, SPR, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
種反応性Human
アプリケーションELISA, FCM, IF, IP, SPR, WB
宿主種Human
クローン性Monoclonal
アイソタイプIgG1, kappa
クローンIDM5
ターゲット NgR, Nogo receptor, Reticulon-4 receptor, RTN4R, Nogo-66 receptor, NOGOR
エンドトキシンレベル < 10 EU/mg as determined by LAL method.
純度 >95% as determined by SDS-PAGE.
精製 Protein A/G purified from cell culture supernatant.
アクセッション番号 Q9BZR6
RRID

Anti-RTN4R/NgR1/Nogor Antibody (M5) (abinScience Cat# HP096013, RRID:AB_3729079)
_x005F_x000D_

形態 Liquid
保存バッファー 0.01M PBS pH 7.4

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

製品使用情報
アプリケーション 希釈
ELISA 1:2000-1:20000
WB 1:500-1:2000
安定性と保存 Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

Reticulon-4 receptor (RTN4R/NgR1) is a ~50 kDa protein. Receptor for RTN4, OMG and MAG. Functions as a receptor for the sialylated gangliosides GT1b and GM1. Besides, functions as a receptor for chondroitin sulfate proteoglycans. Can also bind heparin. Intracellular signaling cascades are triggered via the coreceptor NGFR.

1. GrandPré, T. et al. (2002) Nature 417, 547-51. PMID: 12037567
2. Wang, KC. et al. (2002) Nature 417, 941-4. PMID: 12068310
3. Liu, BP. et al. (2002) Science (New York, N.Y.) 297, 1190-3. PMID: 12089450
4. Wong, ST. et al. (2002) Nature neuroscience 5, 1302-8. PMID: 12426574
5. Barton, WA. et al. (2003) The EMBO journal 22, 3291-302. PMID: 12839991
6. Teusch, N. et al. (2006) Assay and drug development technologies 4, 133-41. PMID: 16712417
7. Williams, G. et al. (2008) The Journal of biological chemistry 283, 16641-52. PMID: 18411262
8. Budel, S. et al. (2008) The Journal of neuroscience : the official journal of the Society for Neuroscience 28, 13161-72. PMID: 19052207
9. Wills, ZP. et al. (2012) Neuron 73, 466-81. PMID: 22325200
注意事項 For research use only.
Isotype Control Human IgG1 (LALAPG) Recombinant Isotype Control Antibody (HyHEL-10) (HP688307)
Human IgG1 (LALA) Recombinant Isotype Control Antibody (HyHEL-10) (HP688107)
イメージ
  • Anti-RTN4R/NgR1/Nogor Recombinant Antibody (M5)

    SDS-PAGE

    SDS-PAGE for Anti-RTN4R/NgR1/Nogor Antibody (M5)

参考文献
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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