

| Número de catálogo | VK676044 | ||||
|---|---|---|---|---|---|
| Descripción |
Anti-RV-A NSP3 Polyclonal Antibody (VK676044) is a rabbit polyclonal antibody detecting NSP3 in ELISA, IHC, WB. Suitable for Rotavirus A.
Highlights
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| Reactividad de especies | Rotavirus A (RV-A) | ||||
| Aplicaciones | ELISA, IHC, WB | ||||
| Especie huésped | Rabbit | ||||
| Clonalidad | Polyclonal | ||||
| Isotipo | IgG | ||||
| Inmunógeno | E. coli - derived recombinant RV-A NSP3 (Asp71-Ala277). | ||||
| Objetivo | translation effector protein NSP3, NSP3 | ||||
| Nivel de endotoxinas | Please contact with the lab for this information. | ||||
| Purificación | Purified by antigen affinity column. | ||||
| Número de acceso | P03536, A2T3N5, Q00721 | ||||
| Forma | Liquid | ||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Fondo | Non-structural protein 3 (NSP3) is a ~36 kDa protein. Plays an important role in stimulating the translation of viral mRNAs. These mRNAs are capped but not polyadenylated, instead terminating in a conserved sequence 'GACC' at the 3' that is recognized by NSP3, which competes with host PABPC1 for EIF4G1 binding. The interaction between NSP3 and host EIF4G1 stabilizes the EIF4E-EIF4G1 interaction, thereby facilitating the initiation of capped mRNA translation. | ||||
| Nota | For research use only |
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