

| Número de catálogo | VK101013 |
|---|---|
| Reactividad de especies | Rift valley fever virus (RVFV) |
| Aplicaciones | ELISA, Neutralization, in vivo |
| Especie huésped | Human |
| Clonalidad | Monoclonal |
| Isotipo | IgG1, kappa |
| ID de clon | SAA2775 |
| Objetivo | Envelopment polyprotein, GP, Glycoprotein G1, Glycoprotein N, Gn |
| Nivel de endotoxinas | < 10 EU/mg |
| Pureza | >95% as determined by SDS-PAGE. |
| Purificación | Protein A/G purified from cell culture supernatant. |
| Número de acceso | P21401 |
| Forma | Liquid |
| Buffer de almacenamiento | 0.01M PBS pH 7.4. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
| Envío | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Fondo | Envelopment polyprotein (Gn) is a ~130 kDa protein. Structural component of the virion that interacts with glycoprotein C. It shields the hydrophobic fusion loops of the glycoprotein C, preventing premature fusion. The glycoprotein protrusions are arranged on an icosahedral lattice, with T=12 triangulation. They are able to attach the virion to the host cell receptor CD209/DC-SIGN and to promote fusion of membranes with the late endosome after endocytosis of the virion. Plays a role in the packaging of ribonucleoproteins and polymerase during virus assembly. 1. Freiberg, AN. et al. (2008) Journal of virology 82, 10341-8. PMID: 18715915 2. Halldorsson, S. et al. (2018) Nature communications 9, 349. PMID: 29367607 3. Lozach, PY. et al. (2011) Cell host & microbe 10, 75-88. PMID: 21767814 4. Piper, ME. et al. (2011) PloS one 6, e18070. PMID: 21445316 |
| Nota | For research use only |




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