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Anti-RVFV Glycoprotein Gn Recombinant Antibody (SAA2775) (VK101013)

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概要
カタログ番号VK101013
種反応性Rift valley fever virus (RVFV)
アプリケーションELISA, Neutralization, in vivo
宿主種Human
クローン性Monoclonal
アイソタイプIgG1, kappa
クローンIDSAA2775
ターゲット Envelopment polyprotein, GP, Glycoprotein G1, Glycoprotein N, Gn
エンドトキシンレベル < 10 EU/mg
純度 >95% as determined by SDS-PAGE.
精製 Protein A/G purified from cell culture supernatant.
アクセッション番号 P21401
形態 Liquid
保存バッファー 0.01M PBS pH 7.4.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

発送 In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
安定性と保存 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Envelopment polyprotein (Gn) is a ~130 kDa protein. Structural component of the virion that interacts with glycoprotein C. It shields the hydrophobic fusion loops of the glycoprotein C, preventing premature fusion. The glycoprotein protrusions are arranged on an icosahedral lattice, with T=12 triangulation. They are able to attach the virion to the host cell receptor CD209/DC-SIGN and to promote fusion of membranes with the late endosome after endocytosis of the virion. Plays a role in the packaging of ribonucleoproteins and polymerase during virus assembly.

1. Freiberg, AN. et al. (2008) Journal of virology 82, 10341-8. PMID: 18715915
2. Halldorsson, S. et al. (2018) Nature communications 9, 349. PMID: 29367607
3. Lozach, PY. et al. (2011) Cell host & microbe 10, 75-88. PMID: 21767814
4. Piper, ME. et al. (2011) PloS one 6, e18070. PMID: 21445316
注意事項 For research use only
イメージ
参考文献
Formula
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Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
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