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| カタログ番号 | HV465014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human SCARA5 (Gln118-His495). | ||||||||
| ターゲット | SCARA5, Scavenger receptor hlg, Scavenger receptor class A member 5 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q6ZMJ2 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Scavenger receptor class A member 5 (SCARA5) is a ~53 kDa protein. Ferritin receptor that mediates non-transferrin-dependent delivery of iron. Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non-transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the developing kidney. Preferentially binds ferritin light chain (FTL) compared to heavy chain (FTH1). | ||||||||
| 注意事項 | For research use only. |
Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with SCARA5 antibody (HV465014) at 1 μg/ml.
Lane 1: Recombinant protein
Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (TF690314) at 0.1 μg/mL.
Predict MW: 43 kDa
Observed MW: 43 kDa
Rat Muscle lysates were subjected to SDS PAGE followed by western blot with SCARA5 antibody (HV465014) at 1 μg/ml.
Lane 1: Rat Muscle lysates
Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (TF690314) at 0.1 μg/mL.
Predict MW: 43 kDa
Observed MW: 43 kDa
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