

| Número de catálogo | HT314014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-SCO2 Polyclonal Antibody (HT314014) is a rabbit polyclonal antibody detecting SCO2 in ELISA, IHC, WB. Suitable for Bovine, Human, and Mouse.
Highlights
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| Reactividad de especies | Human | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human SCO2 (Gly42-Ser266). | ||||||||
| Objetivo | Protein SCO2 homolog, mitochondrial, SCO2 | ||||||||
| Nivel de endotoxinas | Please contact with the lab for this information. | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | O43819 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Cytochrome c oxidase assembly factor SCO2 is a ~29 kDa protein. Copper metallochaperone essential for the synthesis and maturation of cytochrome c oxidase subunit II (MT-CO2/COX2); together with SCO1, facilitates the incorporation of copper into the Cu(A) site of MT-CO2/COX2. Could also act as a thiol-disulfide oxidoreductase to regulate the redox state of the cysteines in SCO1 during maturation of MT-CO2/COX2. 1. Leary, SC. et al. (2004) Human molecular genetics 13, 1839-48. PMID: 15229189 2. Leary, SC. et al. (2007) Cell metabolism 5, 9-20. PMID: 17189203 3. Leary, SC. et al. (2009) Human molecular genetics 18, 2230-40. PMID: 19336478 4. Nývltová, E. et al. (2022) Nature communications 13, 3615. PMID: 35750769 | ||||||||
| Nota | For research use only. |
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