

| Numéro de catalogue | HT314014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-SCO2 Polyclonal Antibody (HT314014) is a rabbit polyclonal antibody detecting SCO2 in ELISA, IHC, WB. Suitable for Bovine, Human, and Mouse.
Highlights
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human SCO2 (Gly42-Ser266). | ||||||||
| Cible | Protein SCO2 homolog, mitochondrial, SCO2 | ||||||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | O43819 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Cytochrome c oxidase assembly factor SCO2 is a ~29 kDa protein. Copper metallochaperone essential for the synthesis and maturation of cytochrome c oxidase subunit II (MT-CO2/COX2); together with SCO1, facilitates the incorporation of copper into the Cu(A) site of MT-CO2/COX2. Could also act as a thiol-disulfide oxidoreductase to regulate the redox state of the cysteines in SCO1 during maturation of MT-CO2/COX2. 1. Leary, SC. et al. (2004) Human molecular genetics 13, 1839-48. PMID: 15229189 2. Leary, SC. et al. (2007) Cell metabolism 5, 9-20. PMID: 17189203 3. Leary, SC. et al. (2009) Human molecular genetics 18, 2230-40. PMID: 19336478 4. Nývltová, E. et al. (2022) Nature communications 13, 3615. PMID: 35750769 | ||||||||
| Note | For research use only. |
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