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| カタログ番号 | HT314014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-SCO2 Polyclonal Antibody (HT314014) is a rabbit polyclonal antibody detecting SCO2 in ELISA, IHC, WB. Suitable for Bovine, Human, and Mouse.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human SCO2 (Gly42-Ser266). | ||||||||
| ターゲット | Protein SCO2 homolog, mitochondrial, SCO2 | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | O43819 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Cytochrome c oxidase assembly factor SCO2 is a ~29 kDa protein. Copper metallochaperone essential for the synthesis and maturation of cytochrome c oxidase subunit II (MT-CO2/COX2); together with SCO1, facilitates the incorporation of copper into the Cu(A) site of MT-CO2/COX2. Could also act as a thiol-disulfide oxidoreductase to regulate the redox state of the cysteines in SCO1 during maturation of MT-CO2/COX2. 1. Leary, SC. et al. (2004) Human molecular genetics 13, 1839-48. PMID: 15229189 2. Leary, SC. et al. (2007) Cell metabolism 5, 9-20. PMID: 17189203 3. Leary, SC. et al. (2009) Human molecular genetics 18, 2230-40. PMID: 19336478 4. Nývltová, E. et al. (2022) Nature communications 13, 3615. PMID: 35750769 | ||||||||
| 注意事項 | For research use only. |
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