Anti-SEBOV Glycoprotein GP1 Polyclonal Antibody (VK623034)

Name: Anti-SEBOV Glycoprotein GP1 Polyclonal Antibody
Brand: abinScience
SKU: VK623034
Price: 168 USD
Availability: InStock

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Каталожный номер

VK623034

Описание

Anti-SEBOV GP1 Polyclonal Antibody (VK623034) is a rabbit polyclonal antibody detecting SEBOV GP1 in ELISA, IHC, WB. Suitable for Sudan ebolavirus.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Реактивность видов

Sudan ebolavirus (SEBOV) (Sudan Ebola virus)

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant SEBOV GP1 (Met33-Leu495).

Цель

Envelope glycoprotein, GP, GP1,

Уровень эндотоксинов

Please contact with the lab for this information.

Чистота

>90% as determined by SDS-PAGE.

Очистка

Purified by antigen affinity column.

Номер доступа

Q05320

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000,IHC:1:50-1:500,WB:1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

Envelope glycoprotein (GP1) is a ~74 kDa protein. Trimeric GP1,2 complexes form the virion surface spikes and mediate the viral entry processes, with GP1 acting as the receptor-binding subunit and GP2 as the membrane fusion subunit. At later times of infection, down-regulates the expression of various host cell surface molecules that are essential for immune surveillance and cell adhesion. Down-modulates several integrins including ITGA1, ITGA2, ITGA3, ITGA4, ITGA5, ITGA6, ITGAV and ITGB1. This decrease in cell adhesion molecules may lead to cell detachment, contributing to the disruption of blood vessel integrity and hemorrhages developed during infection (cytotoxicity). Interacts with host TLR4 and thereby stimulates the differentiation and activation of monocytes leading to bystander death of T-lymphocytes.

Примечание

For research use only

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