

| Numéro de catalogue | VK783024 | ||||
|---|---|---|---|---|---|
| Description |
Anti-SEBOV VP40 Polyclonal Antibody (VK783024) is a rabbit polyclonal antibody detecting VP40 in ELISA, IHC, WB. Suitable for Sudan ebolavirus and Reston ebolavirus.
Highlights
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| Reactivité des espèces | Sudan ebolavirus (SEBOV) (Sudan Ebola virus), Reston ebolavirus (REBOV) (Reston Ebola virus) | ||||
| Applications | ELISA, IHC, WB | ||||
| Espèce hôte | Rabbit | ||||
| Clonalité | Polyclonal | ||||
| Isotype | IgG | ||||
| Immunogène | E. coli - derived recombinant SEBOV VP40 (Met44-Gly294). | ||||
| Cible | matrix protein, VP40 | ||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||
| Purification | Purified by antigen affinity column. | ||||
| Numéro d'accès | Q8JPX9, Q5XX06 | ||||
| Forme | Liquid | ||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Contexte | Matrix protein VP40 is a ~35 kDa protein. Plays an essential role virus particle assembly and budding. Acts by interacting with viral ribonucleocapsid and host members of the ESCRT (endosomal sorting complex required for transport) system such as host VPS4, PDCD6IP/ALIX, NEDD4 or TGS101. The interaction with host E3 ubiquitin ligase SMURF2 also facilitates virus budding. May play a role in immune cell dysfunction by being packaged into exosomes that can decrease the viability of recipient cells (via RNAi suppression and exosome-bystander apoptosis). | ||||
| Note | For research use only |
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