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| カタログ番号 | HB391014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-SEC24A Polyclonal Antibody (HB391014) is a rabbit polyclonal antibody detecting Protein transport protein Sec24A; SEC24-related protein A; SEC24A in ELISA, IHC, WB. Suitable for Human, Bovine, and Mouse.
Highlights
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| 種反応性 | Human, Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant human SEC24A (His943-Lys1093). | ||||||||
| ターゲット | Protein transport protein Sec24A; SEC24-related protein A; SEC24A | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | O95486, A6QNT8, Q3U2P1 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Protein transport protein Sec24A is a ~119 kDa protein. Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex. Plays a central role in cargo selection within the COPII complex and together with SEC24B may have a different specificity compared to SEC24C and SEC24D. May package preferentially cargos with cytoplasmic DxE or LxxLE motifs and may also recognize conformational epitopes. 1. Mancias, JD. et al. (2007) Molecular cell 26, 403-14. PMID: 17499046 2. Mancias, JD. et al. (2008) The EMBO journal 27, 2918-28. PMID: 18843296 3. Bonnon, C. et al. (2010) Journal of cell science 123, 1705-15. PMID: 20427317 | ||||||||
| 注意事項 | For research use only |
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